Fig. 4. Expression of mRNAs encoding K_Vs in PC12 cells. (a) The PC12 cells were used in RT-PCR for K_V1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, K_V2.1, 2.2, K_V3.1, 3.2, 3.3, 3.4, K_V4.1, 4.2, 4.3, K_V5.1, K_V6.1, 6.2, 6.3, 6.4, K_V7.1, 7.2, 7.3, 7.4, 7.5, K_V8.1, 8.2, K_V9.1, 9.2, 9.3, K_V10.1, 10.2, K_V11.1, 11.2, 11.3, and K_V12.1, 12.2, 12.3. Data are representative of triplicate experiments. (b) Pharmacological characterization of the endogenous K_V channel in membrane currents of PC12 cells. Effect of Tetraethylammonium (TEA), 4-Aminopyridine (4-AP), and XE-991. Representative recordings showing the effect of TEA (left column), 4-AP (center column), and XE-991 (right column) on endogenous K⁺ currents. (c) The average of inhibition % of K⁺ current (n = 5).